South Africa Travel Vaccinations & Health Advice
Official UK travel immunisation schedule and disease prevention advisory for travellers to South Africa. Book your appointment with accredited local community pharmacies.
Destination Profile
🇿🇦South Africa
4–6 weeks
Prophylaxis Advised
None Needed
MMR & Tetanus
Most Travellers to South Africa
Immunisations strongly advised for nearly all travellers from the UK, regardless of duration of stay.
Hepatitis A
Tetanus
Typhoid
Some Travellers to South Africa
Assessed individually based on itinerary, rural exposure, animal contact, or long stays.
Cholera
Hepatitis B
Measles
Rabies
Tuberculosis
Malaria Prevention for South Africa
Prompt diagnosis and treatment is required as people with malaria can deteriorate quickly. Those at higher risk of malaria, or of severe complications from malaria, include pregnant women, infants and young children, the elderly, travellers who do not have a functioning spleen and those visiting friends and relatives. There is a risk of malaria in the low altitude areas of Mpumalanga and Limpopo particularly those bordering Mozambique, Estwatini and Zimbabwe; this includes the Kruger National Park: atovaquone/proguanil OR doxycycline OR mefloquine recommended during the transmission season, September to May only. In June, July and August, the risk in this area is considered to be very low: awareness of risk and bite avoidance recommended.
Recommended Antimalarial Options:
Atovaquone/Proguanil
Same-day private prescription & dispensing available at accredited clinics.
Doxycycline
Same-day private prescription & dispensing available at accredited clinics.
Mefloquine
Same-day private prescription & dispensing available at accredited clinics.
Book an appointment with an accredited travel health pharmacist for weight-specific dosing and health clearance.
Find Travel Clinic →Entry Requirements for South Africa
None legally required for entry from the United Kingdom
Under International Health Regulations (IHR), an International Certificate of Vaccination or Prophylaxis (ICVP) must be issued by a registered Yellow Fever Vaccination Centre if applicable. Accredited NextDoorClinic community pharmacies can provide ICVP certificates during your consultation.
Book a Travel Vaccination Clinic for South Africa
Find verified GPhC-regulated pharmacies near you offering travel immunisations, Yellow Fever certificates, and antimalarials. Same-day & weekend appointments available.
Clinical Data Source & Attribution:
Travel health advisories and disease risk data are sourced from the National Travel Health Network and Centre (NaTHNaC, Crown Copyright) and TravelHealthPro under the Open Government Licence v3.0. Last reviewed: 2026.
Always consult a qualified travel health pharmacist or healthcare practitioner at an accredited UK clinic to discuss personal medical history, pregnancy, immunosuppression, and itinerary-specific precautions before travelling.